Transcription: Four-panel Gru’s Plan meme. 1st panel: “Decide to make a Gru’s Plan meme.” 2nd panel: “Come up with a sick punchline.” 3rd panel: “Make the last two panels different.” 4th panel: “Get lots of downvotes for some reason.”
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The meme format requires the last two panels to be the same. Gru looking back at it adds a reaction to things not going as planned. Editing the last panel removes this crucial context.
Source: I have a full body Despicable Me tattoo that makes me look like a minion.
True
Memes are supposed to be mutated, combined, and subverted or they are not interesting. A “format” has, on its own, no comedic value and no message. When it comes to memes, changing the format is the format.