The Genesis Open Models Initiative is a U.S. Department of Energy effort to build and release open-weight AI models designed for scientific research. It is hosted through Argonne National Laboratory and is part of the broader DOE Genesis Mission.

What it focuses on

Its main focus is accelerating work in areas such as:

• Energy systems, including grid reliability and nuclear-energy deployment

• Climate and environmental science

• Materials science and chemistry

• Scientific computing, including modernizing high-performance-computing code

• Experiments, simulations, and data analysis

The initiative seeks contributions from universities, labs, companies, and nonprofits—including scientific text, code, datasets, workflow environments, expert task examples, and evaluation methods—to train and assess these models.